SLOAN LAB
Selected Publications
Glioblastoma
Sojka, C., Wang, H.V., Bhatia, T.N., Li, Y., Chopra, P., Sing, A., Voss, A., King, A., Wang, F., Joseph, K., Ravi, V.M., Olson, J., Hoang, K., Nduom, E., Corces, V.G., Yao, B., Sloan, S.A. Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma (2025), Nature Cell Biology​​
​
Sojka, C., Sloan, S.A. Gliomas: a reflection of temporal gliogenic principles (2024), Communications Biology​
​
Darmanis, S.*, Sloan, S.A.*, … Quake, S.A. Single-Cell RNAseq analysis of diffuse neoplastic infiltrating cells at the migrating front of human glioblastoma (2017), Cell Reports *Co-first authors
Glial development and biology
Voss, A..J., Lanjewar, S.N., Sampson, M.M., King, A., Hill, E.J., Sing, A., Sojka, C., Bhatia, T.N., Spangle, J.M., Sloan, S.A. Identification of ligand–receptor pairs that drive human astrocyte development (2023), Nature Neuroscience
​
Lanjewar, S.N., Sloan, S.A. Growing Glia: Cultivating Human Stem Cell Models of Gliogenesis in Health and Disease (2021), Frontiers in Cell and Developmental Biology ​​
​
Sloan, S.A., Huber, N., Caneda, C., …, Barres, B.A., Pasca, S. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells (2017), Neuron
Featured Article Preview NIH Press Release
​​
Brosius Lutz, A., Chung, W., Sloan, S.A., … Barres, B.A., Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury (2017). PNAS
​​
Madelaine, R., Sloan S.A., … Barres, B.A., Mourrain, P. Micro RNA-9 Couples Brain Neurogenesis and Angiogenesis. (2017) Cell Reports
​
Zhang,Y.*, Sloan, S.A.*, Clarke,L., Caneda, C., … Barres, B.A. Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse. (2016), Neuron *Co-first authors
​
Lui, H., Zhang, J., … Sloan, S.A., … Barres, B.A., Huang, E.J. Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation. (2016) Cell
​
Zuchero, B., Fu, M.M., Sloan, S.A., … Barres, B.A. CNS myelin wrapping is driven by myelin basic protein-induced actin disassembly. (2015) Developmental Cell
Organoid bioengineering
Cadena, M., Sing, A., Taylor, K., Jin, L., Ning, L., Salar Amoli, M., Singh, Y., Lanjewar, S. N., Tomov, M. L., Serpooshan, V., & Sloan, S.A. A 3D Bioprinted Cortical Organoid Platform for Modeling Human Brain Development (2024), Advanced Healthcare Materials
​
​Cadena, M., Ning, L.., King, A., Hwang, B., Jin, L,, Serpooshan, V*., Sloan, S.A.* 3D Bioprinting of Neural Tissues (2020), Advanced Healthcare Materials. *Co-corresponding authors
Technique Development
Gupta I., Collier PG*, Haase B., Mahfouz A., Joglekar A., Floyd T., Koopmans F., Barres B., Smit AB, Sloan SA, Luo W., Fredrigo O, Ross ME, Tilgner HU. Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells. (2021) Nature Biotechnology
​
Sloan, S.A., Andersen, J., Birey, F., … Pasca, S. Generation and Assembly of Human Brain Region-Specific 3D Cultures (2018), Nature Protocols
​​
Pasca, A.*, Sloan, S.A.*, Clarke, L., Tian, Y., Makinson, … Barres, B.A., Pasca, S. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D cultures. (2015). Nature Methods *Co-first authors
NIH Press Release Spectrum Key Advances in hIPSC Modeling F1000
​​
Zhang, Y*., Chen, K.*, Sloan, S. A*., Bennett, M. L., Scholze, A. R., … Wu, J. Q. An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex. (2014) The Journal of Neuroscience *Co-first authors
​
Darmanis, S., Sloan, S.A., … Barres, B.A., Quake, S. A survey of human brain transcriptome diversity at the single cell level. (2015) PNAS