SLOAN LAB
Selected Publications
Glioblastoma
Sojka, C., Wang, H.V., Bhatia, T.N., Li, Y., Chopra, P., Sing, A., Voss, A., King, A., Wang, F., Joseph, K., Ravi, V.M., Olson, J., Hoang, K., Nduom, E., Corces, V.G., Yao, B., Sloan, S.A. Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma (2025), Nature Cell Biology
Sojka, C., Sloan, S.A. Gliomas: a reflection of temporal gliogenic principles (2024), Communications Biology
Darmanis, S.*, Sloan, S.A.*, … Quake, S.A. Single-Cell RNAseq analysis of diffuse neoplastic infiltrating cells at the migrating front of human glioblastoma (2017), Cell Reports *Co-first authors
Glial development and biology
Voss, A..J., Lanjewar, S.N., Sampson, M.M., King, A., Hill, E.J., Sing, A., Sojka, C., Bhatia, T.N., Spangle, J.M., Sloan, S.A. Identification of ligand–receptor pairs that drive human astrocyte development (2023), Nature Neuroscience
Lanjewar, S.N., Sloan, S.A. Growing Glia: Cultivating Human Stem Cell Models of Gliogenesis in Health and Disease (2021), Frontiers in Cell and Developmental Biology
Sloan, S.A., Huber, N., Caneda, C., …, Barres, B.A., Pasca, S. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells (2017), Neuron
Featured Article Preview NIH Press Release
Brosius Lutz, A., Chung, W., Sloan, S.A., … Barres, B.A., Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury (2017). PNAS
Madelaine, R., Sloan S.A., … Barres, B.A., Mourrain, P. Micro RNA-9 Couples Brain Neurogenesis and Angiogenesis. (2017) Cell Reports
Zhang,Y.*, Sloan, S.A.*, Clarke,L., Caneda, C., … Barres, B.A. Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse. (2016), Neuron *Co-first authors
Lui, H., Zhang, J., … Sloan, S.A., … Barres, B.A., Huang, E.J. Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation. (2016) Cell
Zuchero, B., Fu, M.M., Sloan, S.A., … Barres, B.A. CNS myelin wrapping is driven by myelin basic protein-induced actin disassembly. (2015) Developmental Cell
Organoid bioengineering
Cadena, M., Sing, A., Taylor, K., Jin, L., Ning, L., Salar Amoli, M., Singh, Y., Lanjewar, S. N., Tomov, M. L., Serpooshan, V., & Sloan, S.A. A 3D Bioprinted Cortical Organoid Platform for Modeling Human Brain Development (2024), Advanced Healthcare Materials
Cadena, M., Ning, L.., King, A., Hwang, B., Jin, L,, Serpooshan, V*., Sloan, S.A.* 3D Bioprinting of Neural Tissues (2020), Advanced Healthcare Materials. *Co-corresponding authors
Technique Development
Gupta I., Collier PG*, Haase B., Mahfouz A., Joglekar A., Floyd T., Koopmans F., Barres B., Smit AB, Sloan SA, Luo W., Fredrigo O, Ross ME, Tilgner HU. Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells. (2021) Nature Biotechnology
Sloan, S.A., Andersen, J., Birey, F., … Pasca, S. Generation and Assembly of Human Brain Region-Specific 3D Cultures (2018), Nature Protocols
Pasca, A.*, Sloan, S.A.*, Clarke, L., Tian, Y., Makinson, … Barres, B.A., Pasca, S. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D cultures. (2015). Nature Methods *Co-first authors
NIH Press Release Spectrum Key Advances in hIPSC Modeling F1000
Zhang, Y*., Chen, K.*, Sloan, S. A*., Bennett, M. L., Scholze, A. R., … Wu, J. Q. An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex. (2014) The Journal of Neuroscience *Co-first authors
Darmanis, S., Sloan, S.A., … Barres, B.A., Quake, S. A survey of human brain transcriptome diversity at the single cell level. (2015) PNAS